AIDS: Virus clones multiply

Keratinocyte Clones Express Chimeric Virus-cell mRNAs

AIDS virus envelope spike structure.

The envelope (Env) spikes on HIV-1 and closely related SIV define the viral tropism, mediate the fusion process and are the prime target of the humoral response. Despite intensive efforts, Env has been slow to reveal its structural and functional secrets. Three gp120 subunits comprise the 'head' of Env and three gp41 subunits comprise the 'stalk' and other membrane-associated elements. The rece...

Television coverage of AIDS and transmission of the AIDS virus.

The introduction of the government framework " The national strategy for sexual health and HIV " 1 is necessary for attempts to prevent sexual causes of premature death and ill health, at a time when transmission of HIV is at a record level and heterosexual intercourse is the most commonly reported mode of transmission. However, policy formation alone will not be effective in the fight against ...

AIDS pacient's long-term battle with multiply recurrent tuberculosis: reinfection or reactivation?

The advent of Mycobacterium tuberculosis strain genotyping has allowed differentiation between disease relapse and exogenous re-infection. We report here a remarkable case of multiply recurrent tuberculosis in a patient living with HIV. Between 1995 and 2009, a young HIV-infected intravenous drug user, who was reluctant to comply with anti-retroviral treatment, underwent at least five tuberculo...

Virus against virus (VIVI): a potential solution against HIV/AIDS

Most therapeutic regimens are aimed at the use of pharmacologic agents or the induction of immunological response against the pathological agent. However, these methods tend to be insufficient for the management of some of the most debilitating infectious diseases. Here we present a novel therapeutic approach. It involves voluntary super-infection of a subject having HIV/AIDS with a virus (GBV-...